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there is also an undifferentiated central integrative mass action, in which the degree of de cit is to a considerable extent in uenced by the size of the lesion Thus a strict division of aphasias into executive and receptive, while still a strong practical concept, is not fully borne out by clinical observation Nevertheless, there are several localizable language functions in the perisylvian cortex Carl Wernicke, of Breslau, Germany, more than any other person, must be credited with the anatomic-psychologic scheme upon which many contemporary ideas of aphasia rest Earlier, Paul Broca (1865), and, even before him, Dax (1836), had made the fundamental observations that a lesion of the insula and the overlying operculum deprived a person of speech and that such lesions were always in the left hemisphere Wernicke s thesis was that there were two major anatomic loci for language: (1) an anterior locus, in the posterior part of the inferior frontal lobe (Broca s area), in which were contained the memory images of speech movements, and (2) the insular region and adjoining parts of the posterior perisylvian cortex, in which were contained the images of sounds (Meynert had already shown that aphasia could occur with lesions in the temporal lobe, Broca s area being intact) Wernicke believed that the bers between these regions ran in the insula and mediated the psychic re ex arc between the heard and spoken word Later, Wernicke came to accept von Monakow s view that the connecting bers ran around the posterior end of the sylvian ssure, in the arcuate fasciculus Wernicke gave a comprehensive description of the receptive or sensory aphasia that now bears his name The four main features, he pointed out, were (1) a disturbance of comprehension of spoken language and (2) of written language (alexia), (3) agraphia, and (4) uent paraphasic speech In Broca s aphasia, by contrast, comprehension was intact, but the patient was mute or employed only a few simple words Wernicke also theorized that a lesion interrupting the connecting bers between the two cortical speech areas would leave the patient s comprehension undisturbed but would prevent the intact sound images from exerting an in uence on the choice of words Wernicke proposed that this variety of aphasia be called Leitungsaphasie, or conduction aphasia (called central aphasia by Kurt Goldstein and deep aphasia by Martin and Saffran) Careful case analyses since the time of Broca and Wernicke have repeatedly borne out these associations between a receptive (Wernicke) type of aphasia and lesions in the posterior perisylvian region and between a predominantly (Broca) motor aphasia and lesions in the posterior part of the inferior frontal lobe and the adjacent, insular, and opercular regions of the frontal cortex The concept of a conduction aphasia, based on an interruption of pathways between Wernicke s and Broca s zones, has been the most dif cult to accept, because it presupposes a neat separation of sensory and motor functions, which is not in line with contemporary views of sensorimotor physiology of the rest of the nervous system or with the recent analyses of language by cognitive neuropsychologists (Margolin) Nevertheless, there are in the medical literature a number of descriptions and we have certainly encountered cases that conform to the Wernicke model of conduction aphasia; the lesion in these cases may lie in the parietal operculum, involving the white matter deep to the supramarginal gyrus, where it presumably interrupts the arcuate fasciculus and posterior insular subcortex (this issue is discussed further on) How these regions of the brain are organized into separable but interactive modules and how they can be activated and controlled by a variety of visual and auditory stimuli and frontal mo-.

Although this magazine is aimed at Unix (specifically Solaris and AIX), this magazine often includes examples of text processing and includes a regular column written by Aeleen Frisch on integrating Windows and Windows NT into a Unix environment called NTegration This often includes script examples that help to bridge the gap between the two platforms A sister publication, WebServer Online Magazine, concentrates on the web production process

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