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tionality, no consistent autonomic or endocrine dysfunction has been demonstrated except perhaps for diminished responses of growth hormone in panic disorders This has been disappointing, since Cannon, with his emergency theory of sympathoadrenal action, had provided such a promising concept of the neurophysiology of acute emotion, and Selye had extended this theory so plausibly to explain all the reactions to stress in animals and humans According to these theories, strong emotion, such as anger or fear, excites the sympathetic nervous system and the adrenal cortex [via corticotropin releasing factor (CRF) and adrenocorticotropic hormone (ACTH)], which are under direct neural as well as endocrine control These sympathoadrenal reactions are brief and sustain the animal in ight or ght (pages 443 and 447) Animals deprived of adrenal cortex or human beings with Addison disease cannot tolerate stress because they are incapable of mobilizing both the adrenal medulla and adrenal cortex Prolonged stress and production of ACTH activates all the adrenal hormones, referred to collectively as steroids (glucocorticoids, mineralocorticoids, and adrenocorticoids) In animals, exercise, cold, oxygen lack, and surgical injury are all said to evoke the same sympathoadrenal reactions as anger or fear Selye s extension of Cannon s theory to his more comprehensive theory of stress, although attractive, has received little support Critics have pointed out that the conditions to which his experimental animals had been subjected are so different from human disease that conclusions as to the similarities of the two cannot be drawn More critical studies of the anatomy and physiology of the hypothalamus, hypophysis, adrenal glands, and autonomic nervous system are still needed to fully test these hypotheses

Figure 7-9

With few exceptions, such as testing pupillary reactions and examination of the skin for abnormalities of color and sweating, the neurologist tends to be casual in evaluating the function of the autonomic nervous system Nonetheless, several simple but informative tests can be used to con rm one s clinical impressions and to elicit abnormalities of autonomic function that may aid in diagnosis A combination of tests is usually necessary, because certain ones are particularly sensitive to abnormalities of sympathetic function and others to parasympathetic or baroreceptor afferent function These are described below and are summarized in Table 26-1 A scheme for the examination of pupillary abnormalities has been presented in Fig 14-8 Responses of Blood Pressure and Heart Rate to Changes in Posture and Breathing These are among the simplest and most important tests of autonomic function and are currently automated in most laboratories McLeod and Tuck state that in changing from the recumbent to the standing position, a fall of more than 30 mmHg systolic and 15 mmHg diastolic is abnormal; others give gures of 20 and 10 mmHg They caution that the arm on which the cuff is placed must be held horizontally when standing, so that the decline in arm pressure will not be obscured by the added hydrostatic pressure The main cause of an orthostatic drop in blood pressure is hypovolemia In the context of recurrent fainting, however, an excessive drop re ects inadequate sympathetic vasoconstrictor activity The use of a tilt table, as described on page 330, is the most sensitive means of inducing orthostatic changes and also elicits

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That may have seemed like a lot of work to get two input forms to look the same, but the point is that with CSS, once the style is completed, you can apply it to any web control or Web form and achieve a consistent design To see how this works, add a CheckBoxList and a Button from the Standard Toolbox menu Apply the CssClass property input to both, and test the application Figure 7-12 shows them all to have the same design now This should give you a better idea of what can be done with CSS and your application

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