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ralysis results in vasodilatation of skin vessels and a rise in skin temperature; vasoconstriction lowers the temperature With a skin thermometer, one may compare affected and normal areas under standard conditions The normal skin temperature is 31 to 33 C when the room temperature is 26 to 27 C Vasoconstrictor tone may also be tested by measuring the reduction in skin temperature at a distant site before and after immersing one or both hands in cold water (see the discussion of the cold pressor test, below) The integrity of the sympathetic re ex arc which includes baroreceptors in the aorta and carotid sinus, their afferent pathways, the vasomotor centers, and the sympathetic and parasympathetic out ow can be tested in a general way by combining the cold pressor test, grip test, mental arithmetic test, and Valsalva maneuver, as described below

{y} - f"zlla}

Vasoconstriction induces an elevation of the blood pressure This is the basis of the cold pressor test In normal persons, immersing one hand in ice water for 1 to 5 min raises the systolic pressure by 15 to 20 mmHg and the diastolic pressure by 10 to 15 mmHg Similarly, the sustained isometric contraction of a group of muscles (eg, those of the forearm in handgrip) for 5 min normally increases the heart rate and the systolic and diastolic pressures by at least 15 mmHg The response in both of these tests is reduced or absent with lesions of the sympathetic re ex arc, particularly of the efferent limb, but neither of these tests has been well quantitated or validated The stress involved in doing mental arithmetic in noisy and distracting surroundings will also stimulate a mild but measurable increase in pulse rate and blood pressure Obviously this response does not depend on the afferent limb of

7:

Matrix algebracan then be usedto manipulatethis vector to computeboth the coefficient of determination and the standard error of the estimate illustratedin the following example as

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As any designer can tell you, far more is involved in design than getting the colors right However, poor colors can ruin an otherwise good design As mentioned, take a look at some designs created by designers to see all of the different considerations you might want to think about when creating your style sheets